logo
  • SELECT LICENSE :

  • US $4,299.00
  • US $8,599.00

Bone Graft Substitutes Market, By Technology (Allografts, Synthetics) By Application (Craniomaxillofacial, Dental, Foot and Ankle, Joint Reconstruction, Long Bone, Spinal Fusion) opportunities and forecast 2020-2027

  • DLR2206
  • 21 September, 2020
  • Pharma & Healthcare
  • Pages: 120
  • Global
Market Overview

Bone grafts and substitutes are extensively used in orthopedic surgeries for frequent applications. Increasing cases of orthopedic complications caused due to the weakened bones are likely to fuel the demand. According to Department of Economic and Social Affairs, UN, Population Division, number of people aged above 60 was 841 million in the year 2013 and is expected to reach almost 2 billion in 2050. Therefore, the number of orthopedic surgeries is anticipated to grow with the rising geriatric population susceptible to orthopedic ailments. Hence, the market is anticipated to witness the significant demand during forecast period.

Furthermore, the increasing number of these spinal fusion surgeries is further fuelling the demand. According to CDC report about 32% of adult population and 60% of elderly population was affected by the spinal deformities as of 2017 with around 488,000 spinal processes performed in the U.S. The common cause of the spinal fusion injury found to be includes trauma, falls, road traffic accidents or collisions. Moreover, increasing incidence of fractures is further increasing rate of grafting procedures. According to CDC, the worldwide occurrence of hip fracture is likely to increase by above 240% in women and above 310% in men by 2050.

Segment Overview

Adoption of the allografts over autografts is increasing owing to the properties such as support and osteoconductivity and immediate structural. Furthermore, allografts do not require additional surgery to harvest the bone, which results in the reduced surgery time and also the rapid wound healing. Hence, allografts are the most commonly used in areas including hip, spine, and knee. Thus, the market is projected to grow at a substantial rate during the forecast period.
Spinal fusion accounts for largest revenue share. Spinal fusion is used to correct the defects in small in the spine. According to European Spine Journal 2016, De novo degenerative lumbar scoliosis is a spinal deformity in elderly population that leads to the disability and LBP/leg pain, disc degeneration and spine trauma etc. To curb the problem, spine grafts are being implemented as a technique of treatment of choice.

Regional Overview

North America commanded the largest revenue share in the 2018. Awareness about commercially available products, and the availability of the advanced infrastructure are key factors contributing to the growth. The U.S., is leading global market by creating maximum product demand on the account of high prevalence of the trauma-related injuries and orthopaedic diseases.

Asia Pacific is projected to show lsubstantial growth over the forecast period. Growth can be accredited to the increased medical tourism and the favourable government initiatives. However, stringent regulatory rules limit adoption in some of countries. In South Korea, product should be approved by Korean Food and Drug Administration before marketing. Similarly in case of Australia, the products are regulated by the Therapeutic Goods Administration (TGA). Moreover, the stringent regulatory scenario in Japan in Japan 2019, the allograft market is expected to register rewarding growth in this region in the coming years.

Competitor overview

Some of the key industry players are Medtronic PLC; DePuy Synthes; Nuvasive, Inc.; Inc.; Wright Medical Group N.V.; Orthofix Holdings, AlloSource, Inc.; and Stryker Corp. The major companies are implementing strategies such as collaborations, partnerships, mergers, and acquisitions to support their market position. Stryker, Medtronic, and Depuy Synthes held the major share of the bone grafts & substitutes market.
The entry of the new players especially in synthetic segment is anticipated to boost market growth with enormous untapped opportunities. In Feb 2019, Medtronic launched a Grafton DBM in Japan, which was first-ever DBM in the country. This initiative is anticipated to increase company’s regional penetration. Furthermore, in April 2018, the medical company Medtronic received the U.S. FDA approval for the Infuse Bone Graft for the spine surgeries. This approval is anticipated to increase company’s penetration in the spine surgery.

Key Players
  1. DePuy Synthes;
  2. Medtronic PLC;
  3. Nuvasive, Inc.;
  4. Orthofix Holdings, Inc.;
  5. Wright Medical Group N.V.;
  6. AlloSource, Inc.;
  7. Stryker Corp.
  8. Baxter
  9. Smith & Nephew, Inc.
  10. Zimmer Biomet

Market Segmentation

By Products
  • Allografts
    • Demineralized Bone Matrix
    • Others
  • Synthetic
    • Ceramic
    • Composite
    • Polymer
    • Others
By Application
  • Craniomaxillofacial
  • Dental
  • Foot and Ankle
  • Joint Reconstruction
  • Long Bone
  • Spinal Fusion
By Geography
  • North America
    • US
    • Canada
  • Europe
    • UK
    • Germany
    • France
    • Italy
    • Spain
    • Rest of Europe
  • Asia-Pacific
    • Japan
    • China
    • India
    • Australia
    • South Korea
    • Rest of Asia-Pacific
  • LAMEA
    • Brazil
    • Saudi Arabia
    • UAE
    • Rest of LAMEA


1 Report Prologue 11

    2 Introduction 14

    • 2.1 Definition 14
    • 2.2 Scope of Study 14
    • 2.3 Research Objective 14
    • 2.4 Assumptions & Limitations 14
      • 2.4.1 Assumptions 14
      • 2.4.2 Limitations 15
    • 2.5 Market Structure 15

    3 Research Methodology 16

    • 3.1 Research Process 16
    • 3.2 Primary Research 17
    • 3.3 Secondary Research 17
    • 3.4 Market Size Estimation 17
    • 3.5 Forecast Model 18

    4 Market Dynamics 19

    • 4.1 Introduction 19
    • 4.2 Drivers 20
      • 4.2.1 Increase in the number of bone grafting procedures 20
      • 4.2.2 Ageing population with demand for high quality musculoskeletal function in old age 20
      • 4.2.3 Increasing penetration of orthopaedic speciality hospitals and healthcare insurance 20
    • 4.3 Restraints 21
      • 4.3.1 Risk and complications from bone grafting procedures 21
      • 4.3.2 High cost of bone graft treatment 21
    • 4.4 Opportunities 21
      • 4.4.1 Technological advancements 21
      • 4.4.2 High investment in biotech sector 21
      • 4.4.3 Consolidation of large healthcare providers in the US 22
    • 4.5 Challenges 22
      • 4.5.1 Worsening regulatory landscape in the US 22
      • 4.5.2 Growing cost of noncompliance 22
    • 4.6 Macroeconomic Indicators 23
    • 4.7 Technology Trends & Assessment 24
      • 4.7.1 Bone-graft Materials 24
      • 4.7.2 Recombinant DNA Technology 24
      • 4.7.3 Titanium-foam Implant 24
      • 4.7.4 Customised Degradable Implants 24
      • 4.7.5 Nanotechnology 25

    5 Market Factor Analysis 26

    • 5.1 Porter’s Five Forces Analysis 26
      • 5.1.1 Threat from a New Entrant 26
      • 5.1.2 Bargaining Power of Buyer 27
      • 5.1.3 Bargaining Power of Supplier 28
      • 5.1.4 Threat from substitute 28
      • 5.1.5 Intensity of Competitive Rivalry 28
    • 5.2 Supply Chain Analysis 29
      • 5.2.1 Raw Material 29
      • 5.2.2 Supplier 30
      • 5.2.3 Manufacturer 30
      • 5.2.4 Distributer 31
      • 5.2.5 Customer-Retailer 31
      • 5.2.6 Consumer 31
    • 5.3 Investment Opportunity Analysis 32
      • 5.3.1 Market size, growth rate, and profitability 32
      • 5.3.2 Investment Risks 32
      • 5.3.3 Market Outlook 32
      • 5.3.4 Competitors 33
      • 5.3.5 Projections 33
    • 5.4 Merger & Acquisition Landscape 33

    6 Global Bone Graft Substitute Market, By Type 35

    • 6.1 Introduction 35
    • 6.2 Autograft 37
    • 6.3 Demineralized Bone Matrix 38
    • 6.4 Synthetic Bone Grafts 39
    • 6.5 Bone Morphogenetic Protein 40
    • 6.6 Others 40

    7 Global Bone Graft Substitute Market, By Application 41

    • 7.1 Introduction 41
    • 7.2 Spinal Fusion 43
    • 7.3 Joint Reconstruction 44
    • 7.4 Long Bone 45
    • 7.5 Dental 46
    • 7.6 Foot & Ankle 47
    • 7.7 Others 47

    8 Global Bone Graft Substitute Market, By Region 48

    • 8.1 Introduction 48
    • 8.2 Americas 49
    • 8.3 Europe 60
    • 8.4 Asia Pacific 79
    • 8.5 Middle East & Africa 94

    9 Competitive Landscape 101

    • 9.1 Introduction 101
    • 9.2 Company Share Analysis 102

    10 Company Profiles 103

    • 10.1 ACE Surgical Supply Company, Inc. 103
      • 10.1.1 Company Overview 103
      • 10.1.2 Product Overview 103
      • 10.1.3 Financial Overview 104
      • 10.1.4 Key Development 104
    • 10.2 BioHorizons IPH, Inc. 105
      • 10.2.1 Company Overview 105
      • 10.2.2 Product Overview 105
      • 10.2.3 Financial Overview 105
      • 10.2.4 Key Development 106
      • 10.2.5 SWOT 107
    • 10.3 Dentium Co., Ltd. 108
      • 10.3.1 Company Overview 108
      • 10.3.2 Product Overview 108
      • 10.3.3 Financial Overview 108
      • 10.3.4 Key Development 109
      • 10.3.5 SWOT 109
    • 10.4 Dentsply Sirona 110
      • 10.4.1 Company Overview 110
      • 10.4.2 Product Overview 110
      • 10.4.3 Financial Overview 111
      • 10.4.4 Key Development 112
      • 10.4.5 SWOT Analysis 113
    • 10.5 Institut Straumann AG 114
      • 10.5.1 Company Overview 114
      • 10.5.2 Product Overview 114
      • 10.5.3 Financial Overview 114
      • 10.5.4 Key Development 115
      • 10.5.5 SWOT Analysis 116
    • 10.6 Medtronic plc 117
      • 10.6.1 Company Overview 117
      • 10.6.2 Product Overview 117
      • 10.6.3 Financial Overview 117
      • 10.6.4 Key Development 119
      • 10.6.5 SWOT Analysis 120
    • 10.7 Stryker Corporation 121
      • 10.7.1 Company Overview 121
      • 10.7.2 Product Overview 121
      • 10.7.3 Financial overview 121
      • 10.7.4 Key Development 123
      • 10.7.5 SWOT Analysis 124
    • 10.8 Zimmer Biomet 125
      • 10.8.1 Company Overview 125
      • 10.8.2 Product Overview 125
      • 10.8.3 Financial Overview 125
      • 10.8.4 Key Development 127
      • 10.8.5 SWOT Analysis 128

    11 Conclusion 129

    • 11.1 Key Findings 129
      • 11.1.1 CEO’s Viewpoint 129
      • 11.1.2 Unmet Needs 129
      • 11.1.3 Key Companies To Watch 129
      • 11.1.4 Prediction 129

    Report You Might be Interested